Glucose 6-phosphate dehydrogenase deficiency and cystic fibrosis.
نویسندگان
چکیده
Introduction Cystic fibrosis (CF) occurs in approximately 1 in 2000 Caucasian births, but is rare in other races (di Sant'Agnese and Davis, 1976). In Negroes the incidence is 1 in 17 000 (di Sant'Agnese and Davis, 1976), while cases from the Indian sub-continent are even rarer (Reddy et al., 1969). Glucose 6-phosphate dehydrogenase (G-6PD) deficiency, a sex-linked disorder causing haemolysis primarily in males, occurs mainly in people from Africa, China, the Mediterranean and parts of Asia (Luzzatto, 1975). Although there have been reports of CF in association with a1-antitrypsin deficiency, cri-du-chat syndrome, Kartagener's syndrome, Wiskott-Aldrich syndrome and Down's syndrome (di Sant'Agnese and Davis, 1976), so far as the authors know, the occurrence of both CF and G-6PD-deficiency in the same individual has not been previously reported.
منابع مشابه
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ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 57 669 شماره
صفحات -
تاریخ انتشار 1981